30 Apr 2008

Single-celled bacterium works 24-7

Scientists at Washington University in St. Louis have gained the first detailed insight into the way circadian rhythms govern global gene expression in Cyanothece, a type of cyanobacterium (blue-green algae) known to cycle between photosynthesis during the day and nitrogen fixation at night. In general, this study shows that during the day, Cyanothece increases expression of genes governing photosynthesis and sugar production, as expected. At night, however, Cyanothece ramps up the expression of genes governing a surprising number of vital processes, including energy metabolism, nitrogen fixation, respiration, the translation of messenger RNA (mRNA) to proteins and the folding of these proteins into proper configurations........

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